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The Flavonoid Luteolin, but Not Luteolin-7-O-Glucoside, Prevents a Transthyretin Mediated Toxic Response

Transthyretin (TTR) is a homotetrameric plasma protein with amyloidogenic properties that has been linked to the development of familial amyloidotic polyneuropathy (FAP), familial amyloidotic cardiomyopathy, and senile systemic amyloidosis. The in vivo role of TTR is associated with transport of thy...

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Detalles Bibliográficos
Autores principales: Iakovleva, Irina, Begum, Afshan, Pokrzywa, Malgorzata, Walfridsson, Malin, Sauer-Eriksson, A. Elisabeth, Olofsson, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447256/
https://www.ncbi.nlm.nih.gov/pubmed/26020516
http://dx.doi.org/10.1371/journal.pone.0128222