Statin-Induced Increases in Atrophy Gene Expression Occur Independently of Changes in PGC1α Protein and Mitochondrial Content

One serious side effect of statin drugs is skeletal muscle myopathy. Although the mechanism(s) responsible for statin myopathy remains to be fully determined, an increase in muscle atrophy gene expression and changes in mitochondrial content and/or function have been proposed to play a role. In this...

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Detalles Bibliográficos
Autores principales: Goodman, Craig A., Pol, Derk, Zacharewicz, Evelyn, Lee-Young, Robert S., Snow, Rod J., Russell, Aaron P., McConell, Glenn K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447258/
https://www.ncbi.nlm.nih.gov/pubmed/26020641
http://dx.doi.org/10.1371/journal.pone.0128398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447258/
https://www.ncbi.nlm.nih.gov/pubmed/26020641
http://dx.doi.org/10.1371/journal.pone.0128398

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