Immunological Basis for Rapid Progression of Diabetes in Older NOD Mouse Recipients Post BM-HSC Transplantation

Type I diabetes (T1D), mediated by autoreactive T cell destruction of insulin-producing islet beta cells, has been treated with bone marrow-derived hematopoietic stem cell (BM-HSC) transplantation. Older non-obese diabetic (NOD) mice recipients (3m, at disease-onset stage) receiving syngeneic BM-HSC...

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Detalles Bibliográficos
Autores principales: Wang, Nan, Rajasekaran, Narendiran, Hou, Tieying, Macaubas, Claudia, Mellins, Elizabeth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447290/
https://www.ncbi.nlm.nih.gov/pubmed/26020954
http://dx.doi.org/10.1371/journal.pone.0128494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447290/
https://www.ncbi.nlm.nih.gov/pubmed/26020954
http://dx.doi.org/10.1371/journal.pone.0128494

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