Pseudomonas aeruginosa ExoT Induces Atypical Anoikis Apoptosis in Target Host Cells by Transforming Crk Adaptor Protein into a Cytotoxin

Previously, we demonstrated that Pseudomonas aeruginosa ExoT induces potent apoptosis in host epithelial cells in a manner that primarily depends on its ADP-ribosyltransferase domain (ADPRT) activity. However, the mechanism underlying ExoT/ADPRT-induced apoptosis remains undetermined. We now report...

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Detalles Bibliográficos
Autores principales: Wood, Stephen, Goldufsky, Josef, Shafikhani, Sasha H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447348/
https://www.ncbi.nlm.nih.gov/pubmed/26020630
http://dx.doi.org/10.1371/journal.ppat.1004934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447348/
https://www.ncbi.nlm.nih.gov/pubmed/26020630
http://dx.doi.org/10.1371/journal.ppat.1004934

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