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Dietary Vitamin D(3) Restriction Exacerbates Disease Pathophysiology in the Spinal Cord of the G93A Mouse Model of Amyotrophic Lateral Sclerosis

BACKGROUND: Dietary vitamin D(3) (D(3)) restriction reduces paw grip endurance and motor performance in G93A mice, and increases inflammation and apoptosis in the quadríceps of females. ALS, a neuromuscular disease, causes progressive degeneration of motor neurons in the brain and spinal cord. OBJEC...

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Detalles Bibliográficos
Autores principales: Moghimi, Elnaz, Solomon, Jesse A., Gianforcaro, Alexandro, Hamadeh, Mazen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447353/
https://www.ncbi.nlm.nih.gov/pubmed/26020962
http://dx.doi.org/10.1371/journal.pone.0126355