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Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci

To functionally link coronary artery disease (CAD) causal genes identified by genome wide association studies (GWAS), and to investigate the cellular and molecular mechanisms of atherosclerosis, we have used chromatin immunoprecipitation sequencing (ChIP-Seq) with the CAD associated transcription fa...

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Detalles Bibliográficos
Autores principales: Sazonova, Olga, Zhao, Yuqi, Nürnberg, Sylvia, Miller, Clint, Pjanic, Milos, Castano, Victor G., Kim, Juyong B., Salfati, Elias L., Kundaje, Anshul B., Bejerano, Gill, Assimes, Themistocles, Yang, Xia, Quertermous, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447360/
https://www.ncbi.nlm.nih.gov/pubmed/26020271
http://dx.doi.org/10.1371/journal.pgen.1005202