Summary of the DREAM8 Parameter Estimation Challenge: Toward Parameter Identification for Whole-Cell Models

Whole-cell models that explicitly represent all cellular components at the molecular level have the potential to predict phenotype from genotype. However, even for simple bacteria, whole-cell models will contain thousands of parameters, many of which are poorly characterized or unknown. New algorith...

Descripción completa

Detalles Bibliográficos
Autores principales: Karr, Jonathan R., Williams, Alex H., Zucker, Jeremy D., Raue, Andreas, Steiert, Bernhard, Timmer, Jens, Kreutz, Clemens, Wilkinson, Simon, Allgood, Brandon A., Bot, Brian M., Hoff, Bruce R., Kellen, Michael R., Covert, Markus W., Stolovitzky, Gustavo A., Meyer, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447414/
https://www.ncbi.nlm.nih.gov/pubmed/26020786
http://dx.doi.org/10.1371/journal.pcbi.1004096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447414/
https://www.ncbi.nlm.nih.gov/pubmed/26020786
http://dx.doi.org/10.1371/journal.pcbi.1004096

Ejemplares similares