Cargando…

Whole Genome Sequence of Multiple Myeloma-Prone C57BL/KaLwRij Mouse Strain Suggests the Origin of Disease Involves Multiple Cell Types

Monoclonal gammopathy of undetermined significance (MGUS) is the requisite precursor to multiple myeloma (MM), a malignancy of antibody-producing plasma B-cells. The genetic basis of MGUS and its progression to MM remains poorly understood. C57BL/KaLwRij (KaLwRij) is a spontaneously-derived inbred m...

Descripción completa

Detalles Bibliográficos
Autores principales: Amend, Sarah R., Wilson, William C., Chu, Liang, Lu, Lan, Liu, Pengyuan, Serie, Daniel, Su, Xinming, Xu, Yalin, Wang, Dingyan, Gramolini, Anthony, Wen, Xiao-Yan, O’Neal, Julie, Hurchla, Michelle, Vachon, Celine M., Colditz, Graham, Vij, Ravi, Weilbaecher, Katherine N., Tomasson, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447437/
https://www.ncbi.nlm.nih.gov/pubmed/26020268
http://dx.doi.org/10.1371/journal.pone.0127828