Contemporary evolution of resistance at the major insecticide target site gene Ace-1 by mutation and copy number variation in the malaria mosquito Anopheles gambiae

Functionally constrained genes are ideal insecticide targets because disruption is often fatal, and resistance mutations are typically costly. Synaptic acetylcholinesterase (AChE) is an essential neurotransmission enzyme targeted by insecticides used increasingly in malaria control. In Anopheles and...

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Detalles Bibliográficos
Autores principales: Weetman, David, Mitchell, Sara N, Wilding, Craig S, Birks, Daniel P, Yawson, Alexander E, Essandoh, John, Mawejje, Henry D, Djogbenou, Luc S, Steen, Keith, Rippon, Emily J, Clarkson, Christopher S, Field, Stuart G, Rigden, Daniel J, Donnelly, Martin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447564/
https://www.ncbi.nlm.nih.gov/pubmed/25865270
http://dx.doi.org/10.1111/mec.13197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447564/
https://www.ncbi.nlm.nih.gov/pubmed/25865270
http://dx.doi.org/10.1111/mec.13197

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