Mitochondrial Ca(2+) and membrane potential, an alternative pathway for Interleukin 6 to regulate CD4 cell effector function

IL-6 plays an important role in determining the fate of effector CD4 cells and the cytokines that these cells produce. Here we identify a novel molecular mechanism by which IL-6 regulates CD4 cell effector function. We show that IL-6-dependent signal facilitates the formation of mitochondrial respir...

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Detalles Bibliográficos
Autores principales: Yang, Rui, Lirussi, Dario, Thornton, Tina M, Jelley-Gibbs, Dawn M, Diehl, Sean A, Case, Laure K, Madesh, Muniswamy, Taatjes, Douglas J, Teuscher, Cory, Haynes, Laura, Rincón, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447996/
https://www.ncbi.nlm.nih.gov/pubmed/25974216
http://dx.doi.org/10.7554/eLife.06376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447996/
https://www.ncbi.nlm.nih.gov/pubmed/25974216
http://dx.doi.org/10.7554/eLife.06376

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