The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice

Identification of fluorescent dyes that label the filamentous protein aggregates characteristic of neurodegenerative disease, such as β-amyloid and tau in Alzheimer's disease, in a live cell culture system has previously been a major hurdle. Here we show that pentameric formyl thiophene acetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Brelstaff, Jack, Ossola, Bernardino, Neher, Jonas J., Klingstedt, Therése, Nilsson, K. Peter R., Goedert, Michel, Spillantini, Maria Grazia, Tolkovsky, Aviva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448042/
https://www.ncbi.nlm.nih.gov/pubmed/26074756
http://dx.doi.org/10.3389/fnins.2015.00184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448042/
https://www.ncbi.nlm.nih.gov/pubmed/26074756
http://dx.doi.org/10.3389/fnins.2015.00184

Ejemplares similares