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Molecularly Targeted Therapy of Human Hepatocellular Carcinoma Xenografts with Radio-iodinated Anti-VEGFR2 Murine-Human Chimeric Fab

Vascular endothelial growth factor receptor 2 (VEGFR2) is traditionally regarded as an important therapeutic target in a wide variety of malignancies, such as hepatocellular carcinoma (HCC). We previously generated a murine-human anti-VEGFR2 chimeric Fab (cFab), named FA8H1, which has the potential...

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Detalles Bibliográficos
Autores principales: Huang, Jianfei, Tang, Qi, Wang, Changjun, Yu, Huixin, Feng, Zhenqing, Zhu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448128/
https://www.ncbi.nlm.nih.gov/pubmed/26021484
http://dx.doi.org/10.1038/srep10660