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Toxins Targeting the K(V)1.3 Channel: Potential Immunomodulators for Autoimmune Diseases
Autoimmune diseases are usually accompanied by tissue injury caused by autoantigen-specific T-cells. K(V)1.3 channels participate in modulating calcium signaling to induce T-cell proliferation, immune activation and cytokine production. Effector memory T (T(EM))-cells, which play major roles in many...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448172/ https://www.ncbi.nlm.nih.gov/pubmed/25996605 http://dx.doi.org/10.3390/toxins7051749 |