Cargando…

Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatment

BACKGROUND: The mechanisms allowing residual multiple myeloma (MM) cells to persist after bortezomib (Bz) treatment remain unclear. We hypothesized that studying the biology of bortezomib-surviving cells may reveal markers to identify these cells and survival signals to target and kill residual MM c...

Descripción completa

Detalles Bibliográficos
Autores principales: Adomako, Alfred, Calvo, Veronica, Biran, Noa, Osman, Keren, Chari, Ajai, Paton, James C, Paton, Adrienne W, Moore, Kateri, Schewe, Denis M, Aguirre-Ghiso, Julio A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448210/
https://www.ncbi.nlm.nih.gov/pubmed/26025442
http://dx.doi.org/10.1186/s12885-015-1460-1