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The primary cilium functions as a mechanical and calcium signaling nexus

BACKGROUND: The primary cilium is an antenna-like, nonmotile structure that extends from the surface of most mammalian cell types and is critical for chemosensing and mechanosensing in a variety of tissues including cartilage, bone, and kidney. Flow-induced intracellular calcium ion (Ca(2+)) increas...

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Detalles Bibliográficos
Autores principales: Lee, Kristen L, Guevarra, Marie D, Nguyen, An M, Chua, Mardonn C, Wang, Yingxiao, Jacobs, Christopher R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448211/
https://www.ncbi.nlm.nih.gov/pubmed/26029358
http://dx.doi.org/10.1186/s13630-015-0016-y