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Retrotransposons shape species-specific embryonic stem cell gene expression

Over half of our genome is composed of retrotransposons, which are mobile elements that can readily amplify their copy number by replicating through an RNA intermediate. Most of these elements are no longer mobile but still contain regulatory sequences that can serve as promoters, enhancers or repre...

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Detalles Bibliográficos
Autores principales: Robbez-Masson, Luisa, Rowe, Helen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448215/
https://www.ncbi.nlm.nih.gov/pubmed/26021318
http://dx.doi.org/10.1186/s12977-015-0173-5