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Gastrointestinal delivery of propofol from fospropofol: its bioavailability and activity in rodents and human volunteers

BACKGROUND: Propofol is a safe and widely used intravenous anesthetic agent, for which additional clinical uses including treatment of migraine, nausea, pain and anxiety have been proposed (Vasileiou et al. Eur J Pharmacol 605:1–8, 2009). However, propofol suffers from several disadvantages as a the...

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Detalles Bibliográficos
Autores principales: Wozniak, Krystyna M, Vornov, James J, Mistry, Bipin M, Wu, Ying, Rais, Rana, Slusher, Barbara S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448313/
https://www.ncbi.nlm.nih.gov/pubmed/26021605
http://dx.doi.org/10.1186/s12967-015-0526-9