Posttranslational modifications of α-tubulin in alzheimer disease

BACKGROUND: In Alzheimer disease (AD), hyperphosphorylation of tau proteins results in microtubule destabilization and cytoskeletal abnormalities. Our prior ultra-morphometric studies documented a clear reduction in microtubules in pyramidal neurons in AD compared to controls, however, this reductio...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Su, Bo, Wang, Chunyu, Siedlak, Sandra L., Mondragon-Rodriguez, Siddhartha, Lee, Hyoung-gon, Wang, Xinglong, Perry, George, Zhu, Xiongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448339/
https://www.ncbi.nlm.nih.gov/pubmed/26029362
http://dx.doi.org/10.1186/s40035-015-0030-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448339/
https://www.ncbi.nlm.nih.gov/pubmed/26029362
http://dx.doi.org/10.1186/s40035-015-0030-4

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