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A top-down view of the tumor microenvironment: structure, cells and signaling

It is well established that the tumor microenvironment (TME) contributes to cancer progression. Stromal cells can be divided into mesenchymal, vascular, and immune. Signaling molecules secreted by the tumor corrupts these cells to create “activated” stroma. Equally, the extracellular matrix (ECM) co...

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Detalles Bibliográficos
Autores principales: Bhome, Rahul, Bullock, Marc D., Al Saihati, Hajir A., Goh, Rebecca W., Primrose, John N., Sayan, A. Emre, Mirnezami, Alex H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448519/
https://www.ncbi.nlm.nih.gov/pubmed/26075202
http://dx.doi.org/10.3389/fcell.2015.00033