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Assessing the potential of atomistic molecular dynamics simulations to probe reversible protein-protein recognition and binding
Protein-protein recognition and binding are governed by diffusion, noncovalent forces and conformational flexibility, entangled in a way that only molecular dynamics simulations can dissect at high resolution. Here we exploited ubiquitin’s noncovalent dimerization equilibrium to assess the potential...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448524/ https://www.ncbi.nlm.nih.gov/pubmed/26023027 http://dx.doi.org/10.1038/srep10549 |