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Origin and evolution of lysyl oxidases

Lysyl oxidases (LOX) are copper-dependent enzymes that oxidize primary amine substrates to reactive aldehydes. The best-studied role of LOX enzymes is the remodeling of the extracellular matrix (ECM) in animals by cross-linking collagens and elastin, although intracellular functions have been report...

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Detalles Bibliográficos
Autores principales: Grau-Bové, Xavier, Ruiz-Trillo, Iñaki, Rodriguez-Pascual, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448552/
https://www.ncbi.nlm.nih.gov/pubmed/26024311
http://dx.doi.org/10.1038/srep10568