Single-Dose Local Simvastatin Injection Improves Implant Fixation via Increased Angiogenesis and Bone Formation in an Ovariectomized Rat Model

BACKGROUND: Statins have been reported to promote bone formation. However, taken orally, their bioavailability is low to the bones. Implant therapies require a local repair response, topical application of osteoinductive agents, or biomaterials that promote implant fixation. MATERIAL/METHODS: The pr...

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Detalles Bibliográficos
Autores principales: Tan, Jie, Yang, Ning, Fu, Xin, Cui, Yueyi, Guo, Qi, Ma, Teng, Yin, Xiaoxue, Leng, Huijie, Song, Chunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448596/
https://www.ncbi.nlm.nih.gov/pubmed/25982481
http://dx.doi.org/10.12659/MSM.892247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448596/
https://www.ncbi.nlm.nih.gov/pubmed/25982481
http://dx.doi.org/10.12659/MSM.892247

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