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Contrasting genetic architectures in different mouse reference populations used for studying complex traits

Quantitative trait loci (QTLs) are being used to study genetic networks, protein functions, and systems properties that underlie phenotypic variation and disease risk in humans, model organisms, agricultural species, and natural populations. The challenges are many, beginning with the seemingly simp...

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Detalles Bibliográficos
Autores principales: Buchner, David A., Nadeau, Joseph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448675/
https://www.ncbi.nlm.nih.gov/pubmed/25953951
http://dx.doi.org/10.1101/gr.187450.114