Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing

Although physiological steroid levels are often pulsatile (ultradian), the genomic effects of this pulsatility are poorly understood. By utilizing glucocorticoid receptor (GR) signaling as a model system, we uncovered striking spatiotemporal relationships between receptor loading, lifetimes of the D...

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Detalles Bibliográficos
Autores principales: Stavreva, Diana A., Coulon, Antoine, Baek, Songjoon, Sung, Myong-Hee, John, Sam, Stixova, Lenka, Tesikova, Martina, Hakim, Ofir, Miranda, Tina, Hawkins, Mary, Stamatoyannopoulos, John A., Chow, Carson C., Hager, Gordon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448681/
https://www.ncbi.nlm.nih.gov/pubmed/25677181
http://dx.doi.org/10.1101/gr.184168.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448681/
https://www.ncbi.nlm.nih.gov/pubmed/25677181
http://dx.doi.org/10.1101/gr.184168.114

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