Cargando…
Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing
Although physiological steroid levels are often pulsatile (ultradian), the genomic effects of this pulsatility are poorly understood. By utilizing glucocorticoid receptor (GR) signaling as a model system, we uncovered striking spatiotemporal relationships between receptor loading, lifetimes of the D...
Autores principales: | Stavreva, Diana A., Coulon, Antoine, Baek, Songjoon, Sung, Myong-Hee, John, Sam, Stixova, Lenka, Tesikova, Martina, Hakim, Ofir, Miranda, Tina, Hawkins, Mary, Stamatoyannopoulos, John A., Chow, Carson C., Hager, Gordon L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448681/ https://www.ncbi.nlm.nih.gov/pubmed/25677181 http://dx.doi.org/10.1101/gr.184168.114 |
Ejemplares similares
-
Chromatin accessibility pre-determines glucocorticoid receptor
binding patterns
por: John, Sam, et al.
Publicado: (2011) -
Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation
por: Hakim, Ofir, et al.
Publicado: (2013) -
Overlapping Chromatin Remodeling Systems Collaborate Genome-wide at Dynamic Chromatin Transitions
por: Morris, Stephanie A., et al.
Publicado: (2013) -
Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo
por: Johnson, Thomas A, et al.
Publicado: (2018) -
Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation
por: Thompson, Bethtrice, et al.
Publicado: (2016)