Genetic barcode sequencing for screening altered population dynamics of hematopoietic stem cells transduced with lentivirus

Insertional mutagenesis has been associated with malignant cell transformation in gene therapy protocols, leading to discussions about vector security. Therefore, clonal analysis is important for the assessment of vector safety and its impact on patient health. Here, we report a unique approach to a...

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Detalles Bibliográficos
Autores principales: Zanatta, Daniela B, Tsujita, Maristela, Borelli, Primavera, Aguiar, Rodrigo B, Ferrari, Daniel G, Strauss, Bryan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448734/
https://www.ncbi.nlm.nih.gov/pubmed/26052520
http://dx.doi.org/10.1038/mtm.2014.52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448734/
https://www.ncbi.nlm.nih.gov/pubmed/26052520
http://dx.doi.org/10.1038/mtm.2014.52

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