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DNA vaccination strategy targets epidermal dendritic cells, initiating their migration and induction of a host immune response
The immunocompetence and clinical accessibility of dermal tissue offers an appropriate and attractive target for vaccination. We previously demonstrated that pDNA injection into the skin in combination with surface electroporation (SEP), results in rapid and robust expression of the encoded antigen...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448738/ https://www.ncbi.nlm.nih.gov/pubmed/26052522 http://dx.doi.org/10.1038/mtm.2014.54 |