Cargando…
Promiscuity progression of bioactive compounds over time
In the context of polypharmacology, compound promiscuity is rationalized as the ability of small molecules to specifically interact with multiple targets. To study promiscuity progression of bioactive compounds in detail, nearly 1 million compounds and more than 5.2 million activity records were ana...
Autores principales: | Hu, Ye, Jasial, Swarit, Bajorath, Jürgen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448747/ https://www.ncbi.nlm.nih.gov/pubmed/26064479 http://dx.doi.org/10.12688/f1000research.6473.1 |
Ejemplares similares
-
Determining the Degree of Promiscuity of Extensively Assayed Compounds
por: Jasial, Swarit, et al.
Publicado: (2016) -
Computationally derived compound profiling matrices
por: Vogt, Martin, et al.
Publicado: (2018) -
Extracting Compound Profiling Matrices from Screening
Data
por: Vogt, Martin, et al.
Publicado: (2018) -
Monitoring drug promiscuity over time
por: Hu, Ye, et al.
Publicado: (2014) -
Activity-relevant similarity values for fingerprints and implications for similarity searching
por: Jasial, Swarit, et al.
Publicado: (2016)