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Blockade or deletion of transient receptor potential vanilloid 4 (TRPV4) is not protective in a murine model of sepsis

Sepsis is a systemic inflammatory response triggered by microbial infection that can cause cardiovascular collapse, insufficient tissue perfusion and multi-organ failure. The cation channel transient receptor potential vanilloid 4 (TRPV4) is expressed in vascular endothelium and causes vasodilatatio...

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Detalles Bibliográficos
Autores principales: Sand, Claire A., Starr, Anna, Nandi, Manasi, Grant, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448752/
https://www.ncbi.nlm.nih.gov/pubmed/26064477
http://dx.doi.org/10.12688/f1000research.6298.1