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Is this the right normalization? A diagnostic tool for ChIP-seq normalization

BACKGROUND: Chip-seq experiments are becoming a standard approach for genome-wide profiling protein-DNA interactions, such as detecting transcription factor binding sites, histone modification marks and RNA Polymerase II occupancy. However, when comparing a ChIP sample versus a control sample, such...

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Detalles Bibliográficos
Autores principales: Angelini, Claudia, Heller, Ruth, Volkinshtein, Rita, Yekutieli, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448883/
https://www.ncbi.nlm.nih.gov/pubmed/25957089
http://dx.doi.org/10.1186/s12859-015-0579-z