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Tumor homologous recombination deficiency assays: another step closer to clinical application?

Inherited and acquired defects in homologous recombination, a phenotype termed ‘BRCAness’, may lend to therapeutic exploitation in breast cancer. To this end, development and clinical evaluation of platforms to identify signatures of BRCAness are of immense interest. In this issue of Breast Cancer R...

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Detalles Bibliográficos
Autores principales: Stecklein, Shane R, Sharma, Priyanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448910/
https://www.ncbi.nlm.nih.gov/pubmed/25928813
http://dx.doi.org/10.1186/s13058-014-0409-7