ATP-induced cellular stress and mitochondrial toxicity in cells expressing purinergic P2X7 receptor

Under pathological conditions, the purinergic P2X7 receptor is activated by elevated concentrations of extracellular ATP. Thereby, the receptor forms a slowly dilating pore, allowing cations and, upon prolonged stimulation, large molecules to enter the cell. This process has a strong impact on cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Seeland, Swen, Kettiger, Hélène, Murphy, Mark, Treiber, Alexander, Giller, Jasmin, Kiss, Andrea, Sube, Romain, Krähenbühl, Stephan, Hafner, Mathias, Huwyler, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448979/
https://www.ncbi.nlm.nih.gov/pubmed/26038699
http://dx.doi.org/10.1002/prp2.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448979/
https://www.ncbi.nlm.nih.gov/pubmed/26038699
http://dx.doi.org/10.1002/prp2.123

Ejemplares similares