Cargando…

ATP-induced cellular stress and mitochondrial toxicity in cells expressing purinergic P2X7 receptor

Under pathological conditions, the purinergic P2X7 receptor is activated by elevated concentrations of extracellular ATP. Thereby, the receptor forms a slowly dilating pore, allowing cations and, upon prolonged stimulation, large molecules to enter the cell. This process has a strong impact on cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seeland, Swen, Kettiger, Hélène, Murphy, Mark, Treiber, Alexander, Giller, Jasmin, Kiss, Andrea, Sube, Romain, Krähenbühl, Stephan, Hafner, Mathias, Huwyler, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448979/ https://www.ncbi.nlm.nih.gov/pubmed/26038699 http://dx.doi.org/10.1002/prp2.123

Ejemplares similares

Polymersomes containing quantum dots for cellular imaging
por: Camblin, Marine, et al.
Publicado: (2014)

Engineered nanomaterial uptake and tissue distribution: from cell to organism
por: Kettiger, Helene, et al.
Publicado: (2013)

Tumor targeting using liposomal antineoplastic drugs
por: Huwyler, Jörg, et al.
Publicado: (2008)

The endothelin receptor antagonist macitentan for the treatment of pulmonary arterial hypertension: A cross‐species comparison of its cytochrome P450 induction pattern
por: Treiber, Alexander, et al.
Publicado: (2020)

Reactive Metamizole Metabolites Enhance the Toxicity of Hemin on the ATP Pool in HL60 Cells by Inhibition of Glycolysis
por: Rudin, Deborah, et al.
Publicado: (2020)

ATP release and purinergic signaling in NLRP3 inflammasome activation
por: Gombault, Aurélie, et al.
Publicado: (2013)

Colligative Property of ATP: Implications for Enteric Purinergic Neuromuscular Neurotransmission
por: Chaudhury, Arun, et al.
Publicado: (2016)

Expression Pattern of Purinergic Signaling Components in Colorectal Cancer Cells and Differential Cellular Outcomes Induced by Extracellular ATP and Adenosine
por: Dillard, Clémentine, et al.
Publicado: (2021)

Purinergic Signaling of ATP in COVID-19 Associated Guillain-Barré Syndrome
por: Simões, Júlia Leão Batista, et al.
Publicado: (2021)

Sirtuin 6 Regulates the Activation of the ATP/Purinergic Axis in Endothelial Cells
por: Astigiano, Cecilia, et al.
Publicado: (2023)

Effect of the Purinergic Inhibitor Oxidized ATP in a Model of Islet Allograft Rejection
por: Vergani, Andrea, et al.
Publicado: (2013)

Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions
por: Sui, Guiping, et al.
Publicado: (2013)

Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans
por: Schittny, Andreas, et al.
Publicado: (2021)

ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation
por: Riteau, N, et al.
Publicado: (2012)

Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells
por: Kowal, Justyna M., et al.
Publicado: (2015)

Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism
por: Johansson, Karl E., et al.
Publicado: (2019)

Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2
por: Bachmann, Fabio, et al.
Publicado: (2021)

Abacavir Increases Purinergic P2X7 Receptor Activation by ATP: Does a Pro-inflammatory Synergism Underlie Its Cardiovascular Toxicity?
por: Collado-Díaz, Víctor, et al.
Publicado: (2021)

Ionotropic P2X ATP Receptor Channels Mediate Purinergic Signaling in Mouse Odontoblasts
por: Shiozaki, Yuta, et al.
Publicado: (2017)

Purinergic ATP triggers moxibustion-induced local anti-nociceptive effect on inflammatory pain model
por: Yin, Hai-Yan, et al.
Publicado: (2021)

ATP purinergic receptor signalling promotes Sca-1(+) cell proliferation and migration for vascular remodelling
por: Cui, Yiqin, et al.
Publicado: (2023)

Store-Operated Ca(2+) Entry (SOCE) and Purinergic Receptor-Mediated Ca(2+) Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation
por: Gilbert, Daniel F., et al.
Publicado: (2016)

Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection
por: Séror, Claire, et al.
Publicado: (2011)

Drug-induced ciliogenesis in pancreatic cancer cells is facilitated by the secreted ATP-purinergic receptor signaling pathway
por: Khan, Niamat Ali, et al.
Publicado: (2017)

Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel
por: Rokic, Milos B., et al.
Publicado: (2018)

Correction: ATP purinergic receptor signalling promotes Sca-1 (+) cell proliferation and migration for vascular remodelling
por: Cui, Yiqin, et al.
Publicado: (2023)

Purinergic cotransmission
por: Burnstock, Geoffrey
Publicado: (2009)

Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells
por: Grünig, David, et al.
Publicado: (2018)

Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis
por: Paech, Franziska, et al.
Publicado: (2017)

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
por: Pines, Alex, et al.
Publicado: (2005)

Purinergic signalling in bone
por: Rumney, Robin M. H., et al.
Publicado: (2012)

Purinergic signalling and diabetes
por: Burnstock, Geoffrey, et al.
Publicado: (2013)

Purinergic Signaling in Bone
por: Jørgensen, Niklas Rye, et al.
Publicado: (2013)

Purinergic signalling in neuroregeneration
por: Burnstock, Geoffrey
Publicado: (2015)

Editorial: Purinergic Pharmacology
por: Ciruela, Francisco, et al.
Publicado: (2019)

Purine and purinergic receptors
por: Burnstock, Geoffrey
Publicado: (2018)

Purinergic Signaling in Spermatogenesis
por: Mundt, Nadine, et al.
Publicado: (2022)

Purinergic Signaling in Neuroinflammation
por: Aminin, Dmitry, et al.
Publicado: (2021)

Purinergic Signalling in the Cochlea
por: Vlajkovic, Srdjan M., et al.
Publicado: (2022)

Selective stimulation of catecholamine release from bovine adrenal chromaffin cells by an ionotropic purinergic receptor sensitive to 2-methylthio ATP
por: Tomé, Ângelo R, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_eal06i8bisstblik09nris99ed