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A novel 2-decenoic acid thioester ameliorates corticosterone-induced depression- and anxiety-like behaviors and normalizes reduced hippocampal signal transduction in treated mice

We characterized mice administered corticosterone (CORT) at a dose of 20 mg/kg for 3 weeks to determine their suitability as a model of mood disorders and found that the time immobilized in the tail suspension test was longer and the time spent in the open arms of the elevated plus-maze test was sho...

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Detalles Bibliográficos
Autores principales: Shibata, Shoyo, Iinuma, Munekazu, Soumiya, Hitomi, Fukumitsu, Hidefumi, Furukawa, Yoshiko, Furukawa, Shoei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448981/
https://www.ncbi.nlm.nih.gov/pubmed/26038707
http://dx.doi.org/10.1002/prp2.132