LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a new class of oral anti-diabetic agents that improve glycemic control by inhibiting SGLT2-mediated renal glucose reabsorption. Currently available agents increase urinary glucose excretion (UGE) to <50% of maximal values because they do not i...

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Detalles Bibliográficos
Autores principales: Powell, David R, Smith, Melinda G, Doree, Deon D, Harris, Angela L, Xiong, Wendy W, Mseeh, Faika, Wilson, Alan, Gopinathan, Suma, Diaz, Damaris, Goodwin, Nicole C, Harrison, Bryce, Strobel, Eric, Rawlins, David B, Carson, Ken, Zambrowicz, Brian, Ding, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448982/
https://www.ncbi.nlm.nih.gov/pubmed/26038705
http://dx.doi.org/10.1002/prp2.129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448982/
https://www.ncbi.nlm.nih.gov/pubmed/26038705
http://dx.doi.org/10.1002/prp2.129

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