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Metformin protects primary rat hepatocytes against oxidative stress-induced apoptosis

The majority of chronic liver diseases are accompanied by oxidative stress, which induces apoptosis in hepatocytes and liver injury. Recent studies suggest that oxidative stress and insulin resistance are important in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) and the pathophysiolo...

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Detalles Bibliográficos
Autores principales: de la Rosa, Laura Conde, Vrenken, Titia E, Buist-Homan, Manon, Faber, Klaas Nico, Moshage, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448984/
https://www.ncbi.nlm.nih.gov/pubmed/26038701
http://dx.doi.org/10.1002/prp2.125