Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity

Immune mediated adverse drug reactions (IM-ADRs) remain a significant source of patient morbidity that have more recently been shown to be associated with specific class I and/or II human leukocyte antigen (HLA) alleles. Abacavir-induced hypersensitivity syndrome is a CD8(+) T cell dependent IM-ADR...

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Detalles Bibliográficos
Autores principales: Metushi, Imir G., Wriston, Amanda, Banerjee, Priyanka, Gohlke, Bjoern Oliver, English, A. Michelle, Lucas, Andrew, Moore, Carrie, Sidney, John, Buus, Soren, Ostrov, David A., Mallal, Simon, Phillips, Elizabeth, Shabanowitz, Jeffrey, Hunt, Donald F., Preissner, Robert, Peters, Bjoern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449000/
https://www.ncbi.nlm.nih.gov/pubmed/26024233
http://dx.doi.org/10.1371/journal.pone.0124878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449000/
https://www.ncbi.nlm.nih.gov/pubmed/26024233
http://dx.doi.org/10.1371/journal.pone.0124878

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