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The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation

Epstein-Barr virus (EBV) is a γ-herpesvirus that may cause infectious mononucleosis in young adults. In addition, epidemiological and molecular evidence links EBV to the pathogenesis of lymphoid and epithelial malignancies. EBV has the unique ability to transform resting B cells into permanently pro...

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Detalles Bibliográficos
Autores principales: Friberg, Anders, Thumann, Sybille, Hennig, Janosch, Zou, Peijian, Nössner, Elfriede, Ling, Paul D., Sattler, Michael, Kempkes, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449002/
https://www.ncbi.nlm.nih.gov/pubmed/26024477
http://dx.doi.org/10.1371/journal.ppat.1004910