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The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation
Epstein-Barr virus (EBV) is a γ-herpesvirus that may cause infectious mononucleosis in young adults. In addition, epidemiological and molecular evidence links EBV to the pathogenesis of lymphoid and epithelial malignancies. EBV has the unique ability to transform resting B cells into permanently pro...
Autores principales: | Friberg, Anders, Thumann, Sybille, Hennig, Janosch, Zou, Peijian, Nössner, Elfriede, Ling, Paul D., Sattler, Michael, Kempkes, Bettina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449002/ https://www.ncbi.nlm.nih.gov/pubmed/26024477 http://dx.doi.org/10.1371/journal.ppat.1004910 |
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