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Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors

Lentivirus-based gene delivery vectors carrying multiple gene cassettes are powerful tools in gene transfer studies and gene therapy, allowing coexpression of multiple therapeutic factors and, if desired, fluorescent reporters. Current strategies to express transgenes and microRNA (miRNA) clusters f...

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Detalles Bibliográficos
Autores principales: Askou, Anne Louise, Aagaard, Lars, Kostic, Corinne, Arsenijevic, Yvan, Hollensen, Anne Kruse, Bek, Toke, Jensen, Thomas Gryesten, Mikkelsen, Jacob Giehm, Corydon, Thomas Juhl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449022/
https://www.ncbi.nlm.nih.gov/pubmed/26052532
http://dx.doi.org/10.1038/mtm.2014.64