RhoC and ROCKs regulate cancer cell interactions with endothelial cells

RhoC is a member of the Rho GTPase family that is implicated in cancer progression by stimulating cancer cell invasiveness. Here we report that RhoC regulates the interaction of cancer cells with vascular endothelial cells (ECs), a crucial step in the metastatic process. RhoC depletion by RNAi reduc...

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Detalles Bibliográficos
Autores principales: Reymond, Nicolas, Im, Jae Hong, Garg, Ritu, Cox, Susan, Soyer, Magali, Riou, Philippe, Colomba, Audrey, Muschel, Ruth J., Ridley, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449123/
https://www.ncbi.nlm.nih.gov/pubmed/25677806
http://dx.doi.org/10.1016/j.molonc.2015.01.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449123/
https://www.ncbi.nlm.nih.gov/pubmed/25677806
http://dx.doi.org/10.1016/j.molonc.2015.01.004

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