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RhoC and ROCKs regulate cancer cell interactions with endothelial cells
RhoC is a member of the Rho GTPase family that is implicated in cancer progression by stimulating cancer cell invasiveness. Here we report that RhoC regulates the interaction of cancer cells with vascular endothelial cells (ECs), a crucial step in the metastatic process. RhoC depletion by RNAi reduc...
Autores principales: | Reymond, Nicolas, Im, Jae Hong, Garg, Ritu, Cox, Susan, Soyer, Magali, Riou, Philippe, Colomba, Audrey, Muschel, Ruth J., Ridley, Anne J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449123/ https://www.ncbi.nlm.nih.gov/pubmed/25677806 http://dx.doi.org/10.1016/j.molonc.2015.01.004 |
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