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Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis

BACKGROUND: Chronic Hepatitis B virus (HBV) infection can lead to the development of chronic hepatitis, cirrhosis and hepatocellular carcinoma. We hypothesized that HBV might accelerate hepatocyte ageing and investigated the effect of HBV on hepatocyte cell cycle state and biological age. We also in...

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Detalles Bibliográficos
Autores principales: Tachtatzis, Phaedra M., Marshall, Aileen, Aravinthan, Aloysius, Verma, Suman, Penrhyn-Lowe, Sue, Mela, Marianna, Scarpini, Cinzia, Davies, Susan E., Coleman, Nicholas, Alexander, Graeme J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449162/
https://www.ncbi.nlm.nih.gov/pubmed/26024529
http://dx.doi.org/10.1371/journal.pone.0127511