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Phosphatidylcholine Specific PLC-Induced Dysregulation of Gap Junctions, a Robust Cellular Response to Environmental Toxicants, and Prevention by Resveratrol in a Rat Liver Cell Model

Dysregulation of gap junctional intercellular communication (GJIC) has been associated with different pathologies, including cancer; however, molecular mechanisms regulating GJIC are not fully understood. Mitogen Activated Protein Kinase (MAPK)-dependent mechanisms of GJIC-dysregulation have been we...

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Detalles Bibliográficos
Autores principales: Sovadinova, Iva, Babica, Pavel, Böke, Hatice, Kumar, Esha, Wilke, Andrew, Park, Joon-Suk, Trosko, James E., Upham, Brad L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449167/
https://www.ncbi.nlm.nih.gov/pubmed/26023933
http://dx.doi.org/10.1371/journal.pone.0124454