Trans-Activation between EphA and FGFR Regulates Self-Renewal and Differentiation of Mouse Embryonic Neural Stem/Progenitor Cells via Differential Activation of FRS2α

Ephs and FGFRs belong to a superfamily of receptor tyrosine kinases, playing important roles in stem cell biology. We previously reported that EphA4 and FGFR form a heterodimer following stimulation with ligands, trans-activating each other and signaling through a docking protein, FRS2α, that binds...

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Detalles Bibliográficos
Autores principales: Sawada, Takahiro, Arai, Daiki, Jing, Xuefeng, Furushima, Kenryo, Chen, Qingfa, Kawakami, Kazuki, Yokote, Hideyuki, Miyajima, Masayasu, Sakaguchi, Kazushige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449203/
https://www.ncbi.nlm.nih.gov/pubmed/26024354
http://dx.doi.org/10.1371/journal.pone.0128826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449203/
https://www.ncbi.nlm.nih.gov/pubmed/26024354
http://dx.doi.org/10.1371/journal.pone.0128826

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