A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2

Drugs currently used for treating Parkinson's disease patients provide symptomatic relief without altering the neurodegenerative process. Our aim was to examine the possibility of using DJ-1 (PARK7), as a novel therapeutic target for Parkinson's disease. We designed a short peptide, named...

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Detalles Bibliográficos
Autores principales: Lev, Nirit, Barhum, Yael, Ben-Zur, Tali, Aharony, Israel, Trifonov, Lena, Regev, Noa, Melamed, Eldad, Gruzman, Arie, Offen, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449207/
https://www.ncbi.nlm.nih.gov/pubmed/26024237
http://dx.doi.org/10.1371/journal.pone.0127549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449207/
https://www.ncbi.nlm.nih.gov/pubmed/26024237
http://dx.doi.org/10.1371/journal.pone.0127549

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