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Cell proliferation is a key determinant of the outcome of FOXO3a activation
The FOXO family of forkhead transcription factors have a pivotal role in determining cell fate in response to oxidative stress. FOXO activity can either promote cell survival or induce cell death. Increased FOXO-mediated cell death has been implicated in the pathogenesis of degenerative diseases aff...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449364/ https://www.ncbi.nlm.nih.gov/pubmed/25935481 http://dx.doi.org/10.1016/j.bbrc.2015.04.112 |