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Cell proliferation is a key determinant of the outcome of FOXO3a activation

The FOXO family of forkhead transcription factors have a pivotal role in determining cell fate in response to oxidative stress. FOXO activity can either promote cell survival or induce cell death. Increased FOXO-mediated cell death has been implicated in the pathogenesis of degenerative diseases aff...

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Detalles Bibliográficos
Autores principales: Poulsen, Raewyn C., Carr, Andrew J., Hulley, Philippa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449364/
https://www.ncbi.nlm.nih.gov/pubmed/25935481
http://dx.doi.org/10.1016/j.bbrc.2015.04.112