Cargando…
Cell proliferation is a key determinant of the outcome of FOXO3a activation
The FOXO family of forkhead transcription factors have a pivotal role in determining cell fate in response to oxidative stress. FOXO activity can either promote cell survival or induce cell death. Increased FOXO-mediated cell death has been implicated in the pathogenesis of degenerative diseases aff...
Autores principales: | Poulsen, Raewyn C., Carr, Andrew J., Hulley, Philippa A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449364/ https://www.ncbi.nlm.nih.gov/pubmed/25935481 http://dx.doi.org/10.1016/j.bbrc.2015.04.112 |
Ejemplares similares
-
Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence
por: Poulsen, Raewyn C, et al.
Publicado: (2014) -
Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure
por: Poulsen, R C, et al.
Publicado: (2014) -
Lovastatin‐Mediated Changes in Human Tendon Cells
por: Kuzma‐Kuzniarska, Maria, et al.
Publicado: (2015) -
Regulation of Hypoxia-Induced Cell Death in Human Tenocytes
por: Liang, Min, et al.
Publicado: (2012) -
A New Method to Sort Differentiating Osteoclasts into Defined Homogeneous Subgroups
por: Hulley, Philippa A., et al.
Publicado: (2022)