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Release of 5-Aminosalicylic Acid (5-ASA) from Mesalamine Formulations at Various pH Levels

INTRODUCTION: Oral formulations of 5-aminosalicylic acid (5-ASA) for treatment of ulcerative colitis have been developed to minimize absorption prior to the drug reaching the colon. In this study, we investigate the release of 5-ASA from available oral mesalamine formulations in physiologically rele...

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Detalles Bibliográficos
Autores principales: Abinusawa, Adeyinka, Tenjarla, Srini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449368/
https://www.ncbi.nlm.nih.gov/pubmed/25951927
http://dx.doi.org/10.1007/s12325-015-0206-4