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In vitro activity and in vivo efficacy of a combination therapy of diminazene and chloroquine against murine visceral leishmaniasis

The present study evaluated the in vitro activity and in vivo efficacy of diminazene combined with chloroquine as a potential drug against Leishmania donovani. Amphotericin B was used as a positive control drug. In vitro activity involved incubation of various drug concentrations with promastigotes...

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Detalles Bibliográficos
Autores principales: Mwololo, Samuel W, Mutiso, Joshua M, Macharia, John C, Bourdichon, Alain J, Gicheru, Michael M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449489/
https://www.ncbi.nlm.nih.gov/pubmed/26060445
http://dx.doi.org/10.7555/JBR.29.20140072